Nucleic acids 40% and Co-enzyme 4% (Nicotinamide Adenine Dinucleotide- Nucleic acids Salt)
Nucleic acids have become an important nutritional supplement in poultry feed; however, the digestion of nucleic acids in poultry is unclear. The objective of this study was to investigate the digestion of nucleic acids by chicken pepsin in vitro.
The extracted pepsinogen from the stomach of the chicken was purified to homogeneity. Upon activation at pH 4.0, chicken pepsinogen was converted to its active form
Interestingly, the digestion of the nucleic acids was inhibited when pepsin was treated by alkaline solution (pH 8.0) or pepstatin A. Also, the digestion of the nucleic acids was not affected by the addition of haemoglobin or bovine serum albumin.
The results suggested that nucleic acids could be digested by chicken pepsin. Thus pepsin may have a role in digesting nucleic acids in vivo. Nucleic acids added to poultry fed may be digested, starting from the stomach.
Dosage: 1-3 kg per MT of Feed